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| Sophomoric | juvenile; immature |
| Soporific | inducing sleep |
| Sparse | spare; bare; meager |
| Specious | FALSE |
| Speckled | spotted; freckled; dotted |
| Sporadic | not continuous; intermittent |
| Spurious | FALSE |
| Stagnant | still; not moving |
| Staid | dull; sober; serious |
| Stanza | section of a poem |
| Staunch | loyal; faithful; dependable |
| Stereotype | fixed image |
| Stevedore | dockworker |
| Stifle | suppress |
| Stoic | known for fortitude; indifferent to pleasure or pain |
| Stoke | add fuel to; strengthen |
| Stolid | impassive; dull; indifferent |
| Stratagem | plot; plan; trick |
| Strident | loud and harsh |
| Stringent | strict or severe |